3,4-Methylenedioxyphentermine

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3,4-Methylenedioxyphentermine (3,4-MDP), also known as 3,4-MDPEN, is a lesser-known psychedelic drug. It is the N-ethyl analog of 3,4-methylenedioxyamphetamine (MDA). 3,4-MDP was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines I Have Known and Loved), the minimum dosage is listed as 150 mg, and the duration unknown. 3,4-MDP produces few to no effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of 3,4-MDP.

Chemistry[edit | edit source]

3,4-Methylenedioxyphentermine, or 3,4-MDP, is a substituted amphetamine. It is structurally similar to amphetamine, methamphetamine, and other phenethylamine derivatives. The compound is formed by adding a methylenedioxy functional group to the phenethylamine backbone. This modification enhances the pharmacological activity of the compound.

Pharmacology[edit | edit source]

The pharmacological mechanisms of 3,4-MDP are not well understood. It is believed to act as a serotonin and norepinephrine releasing agent, similar to other substituted amphetamines. However, due to the lack of research on this compound, this is purely speculative.

Effects[edit | edit source]

The effects of 3,4-MDP are largely unknown due to the lack of human studies. In Shulgin's book, he reports that the compound produces few to no effects. However, this may be due to the low dosage used in his experiments.

Legal Status[edit | edit source]

The legal status of 3,4-MDP varies by country. In the United States, it is not specifically listed as a controlled substance, but it may be considered an analog of other controlled substances, making its sale or possession potentially illegal under the Federal Analogue Act.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD