4-HO-5-MeO-DMT

4-HO-5-MeO-DMT

4-HO-5-MeO-DMT is a psychedelic tryptamine compound and is a structural analog of psilocin. It is not known to occur naturally in any organism and is not typically used recreationally.

Chemistry

4-HO-5-MeO-DMT, or 4-hydroxy-5-methoxy-N,N-dimethyltryptamine, is a synthetic indole alkaloid molecule of the tryptamine class. Tryptamines share a core structure comprised of a bicyclic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-HO-5-MeO-DMT is substituted at R4 of its indole heterocycle with a hydroxy (HO) functional group OH-. It also contains two methyl groups CH3- bound to the terminal amine RN of the tryptamine backbone (DMT). 4-HO-5-MeO-DMT is the 4-hydroxy analog of 5-MeO-DMT and the N,N-dimethyl analog of 4-HO-5-MeO-MiPT.

Pharmacology

The pharmacological actions of 4-HO-5-MeO-DMT are not well studied. However, it is likely to act as a 5-HT2A receptor agonist, similar to other psychedelic tryptamines. The 5-HT2A receptor is a target for many psychedelic drugs and is thought to be a key player in the cognitive and perceptual effects of these substances.

Effects

The effects of 4-HO-5-MeO-DMT are largely unknown due to the lack of scientific research. Anecdotal reports suggest that it may produce effects similar to other psychedelic tryptamines, including altered perception, enhanced visual imagery, and introspective thought. However, these reports should be taken with caution as they are not backed by scientific evidence.

Legal Status

The legal status of 4-HO-5-MeO-DMT varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of 5-MeO-DMT, which is a Schedule I drug under the Controlled Substances Act.

See Also

• Tryptamine
• Psilocin
• 5-MeO-DMT
• Psychedelic drug