4-Trifluoromethylamphetamine

From WikiMD's Food, Medicine & Wellness Encyclopedia

4-Trifluoromethylamphetamine (also known as 4-TFMA) is a psychoactive drug and research chemical that belongs to the amphetamine class. It is known for its stimulant and entactogen properties.

Chemistry[edit | edit source]

4-Trifluoromethylamphetamine is a substituted amphetamine, which means it is a derivative of the parent compound amphetamine. The chemical structure of 4-TFMA includes a trifluoromethyl group, which is a functional group consisting of three fluorine atoms and one carbon atom, attached to the 4-position of the phenyl ring. This modification results in a significant alteration of the drug's pharmacological properties compared to amphetamine.

Pharmacology[edit | edit source]

The exact mechanism of action of 4-TFMA is not fully understood. However, like other amphetamines, it is believed to work primarily by increasing the levels of certain neurotransmitters in the brain, particularly dopamine, norepinephrine, and serotonin. These neurotransmitters are involved in regulating mood, energy, focus, and feelings of empathy and social connection, which are often enhanced by amphetamine-type drugs.

Effects[edit | edit source]

The effects of 4-TFMA can vary widely depending on the dose, the individual's physiology, and the context in which it is used. Common effects reported by users include increased energy, euphoria, enhanced sociability, and heightened sensory perception. However, it can also cause a range of negative effects, such as anxiety, paranoia, insomnia, and potentially dangerous increases in heart rate and blood pressure.

Legal Status[edit | edit source]

The legal status of 4-TFMA varies by country. In many jurisdictions, it is classified as a controlled substance due to its potential for abuse and its similarity to other, more well-known amphetamines.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD