5-Carboxamidotryptamine

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5-Carboxamidotryptamine (also known as 5-CT) is a tryptamine derivative that is a potent serotonin receptor agonist. It is structurally related to the amino acid tryptophan, as well as the neurotransmitter serotonin.

Chemistry[edit | edit source]

5-Carboxamidotryptamine is a tryptamine derivative, which is a family of compounds structurally derived from the essential amino acid tryptophan. It has a carboxamide group attached to the 5-position of the tryptamine backbone.

Pharmacology[edit | edit source]

5-CT is a potent agonist for the majority of serotonin receptors. It is most commonly used in scientific research to study the function of these receptors, particularly the 5-HT1A receptor and 5-HT2A receptor.

Research and Clinical Significance[edit | edit source]

Due to its potent activity at serotonin receptors, 5-CT has been used in scientific research to understand the role of these receptors in the brain and their potential as targets for the treatment of various disorders. This includes research into conditions such as depression, anxiety disorders, and schizophrenia.

Safety and Toxicity[edit | edit source]

As a potent serotonin receptor agonist, 5-CT has the potential to cause serotonin syndrome, a potentially life-threatening condition caused by excessive activation of serotonin receptors. Therefore, it should be used with caution and under the supervision of a qualified professional.

See Also[edit | edit source]

Template:Serotonin receptor agonists

5-Carboxamidotryptamine Resources
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Contributors: Prab R. Tumpati, MD