5-MeO-NMT

5-MeO-NMT

5-MeO-NMT or 5-Methoxy-N-methyltryptamine is a natural product and psychedelic drug of the tryptamine class. It is found in a wide variety of plant species, and a single psychoactive toad species, the Colorado River toad.

Chemistry

5-MeO-NMT is a member of the 5-Methoxytryptamine family. These are compounds containing a tryptamine moiety, which consists of an indole ring that bears an amino (NH2) group at carbon 1 and a methoxy group at carbon 5. The indole ring is substituted at the 3-position with an ethyl side chain.

Pharmacology

The pharmacology of 5-MeO-NMT is not well known. It is likely to act as a serotonin receptor agonist, similar to other tryptamines, but specific binding data is not available. It is known to be active when administered orally, although it is not commonly used in this manner due to its potent psychoactive effects.

Effects

The effects of 5-MeO-NMT can vary widely depending on the dose, set, and setting. At lower doses, it can produce mild changes in perception, mood, and thought. At higher doses, it can lead to a state of psychedelic trance, with intense visual hallucinations, profound changes in consciousness, and out-of-body experiences.

Legal Status

The legal status of 5-MeO-NMT varies by country. In the United States, it is not specifically listed as a controlled substance, but it may be considered an analog of other controlled tryptamines under the Federal Analogue Act.

See Also

• Tryptamine
• Psychedelic drug
• Serotonin receptor