6-MeO-DMT

Psychedelic tryptamine compound

6-MeO-DMT
INN
Drug class
Routes of administration	Smoked, Insufflated, Oral
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status	Uncontrolled
CAS Number	3188-02-1
PubChem	62158
DrugBank
ChemSpider	55966
KEGG

6-Methoxy-N,N-dimethyltryptamine (6-MeO-DMT) is a psychedelic compound belonging to the tryptamine class. It is structurally related to other psychedelic tryptamines such as 5-MeO-DMT and DMT.

Chemical Structure and Properties

6-MeO-DMT is a synthetic compound with the chemical formula C₁₃H₁₈N₂O. It features a methoxy group at the 6-position of the indole ring, distinguishing it from other tryptamines. The presence of this methoxy group is believed to influence its pharmacological properties.

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Chemical structure of 6-MeO-DMT

Pharmacology

6-MeO-DMT acts primarily as a serotonin receptor agonist, particularly at the [[5-HT_2A receptor]], which is thought to be responsible for its psychedelic effects. The compound may also interact with other serotonin receptors, contributing to its overall psychoactive profile.

Effects

The effects of 6-MeO-DMT are similar to those of other psychedelic tryptamines, inducing alterations in perception, mood, and cognition. Users report visual and auditory hallucinations, changes in time perception, and profound alterations in consciousness. The intensity and duration of effects can vary depending on the route of administration and dosage.

Routes of Administration

6-MeO-DMT can be administered through various routes, including smoking, insufflation, and oral ingestion. Smoking is reported to produce rapid onset of effects, while oral ingestion may result in a longer duration of action.

Legal Status

The legal status of 6-MeO-DMT varies by country. In some jurisdictions, it is classified as a controlled substance, while in others, it remains unregulated. Users should be aware of the legal implications of possessing or using this compound in their region.

Related Compounds

6-MeO-DMT is part of a broader class of psychedelic tryptamines, which includes:

• DMT (N,N-Dimethyltryptamine)
• 5-MeO-DMT (5-Methoxy-N,N-dimethyltryptamine)
• 4-AcO-DMT (4-Acetoxy-N,N-dimethyltryptamine)

See Also

• Psychedelic drug
• Serotonin receptor
• Tryptamine

Related Pages

• List of psychedelic drugs
• Psychedelic therapy