Allograft
allograft (A-loh-graft) The transplant of an organ, tissue, or cells from one individual to another individual of the same species who is not an identical twin. Bone allografts are commercially available from tissue banks.
Freeze-Dried Bone Allograft (FDBA)[edit | edit source]
They are obtained from cortical bone within 12hrs of the death of the donor, defatted, cut in pieces, washed in absolute alcohol, and deep-frozen. The material is then demineralized, ground and sieved to a particle size of 250-750μm and freeze-dried before it is vacuum-sealed in glass vials. It is considered as a osteoconductive material and is slow to resorb and hence used in Guided tissue regeneration.
Demineralized Freeze-Dried Bone Allograft (DFDBA)[edit | edit source]
Demineralization in cold, diluted hydrochloric acid exposes the components of bone matrix, which are closely associated with collagen fibrils and have been termed Bone Morphogenetic Proteins(BMPs). It is considered as a Osteoinductive graft and has a high osteogenic potential than FDBA. Studies have provided strong evidence that DFDBA in periodontal defects result in significant probing depth reduction, attachment level gain, and osseous regeneration. The combination of DFDBA and GTR has also proved to be very successful. However, limitations of the use of DFDBA include the possible although remote, potential of disease transfer from the cadaver.
| Allograft Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
