Androstenediol 17-acetate

From WikiMD's Food, Medicine & Wellness Encyclopedia

Androstenediol 17-acetate is a steroid and androgen that is used in the field of medicine. It is a derivative of androstenediol, with an acetate group attached at the 17th carbon position. This modification enhances the bioavailability of the steroid, allowing it to be more effectively absorbed and utilized by the body.

Chemical Structure[edit | edit source]

The chemical structure of androstenediol 17-acetate is similar to that of other androgens. It consists of a four-ring structure, with the acetate group attached at the 17th carbon position. This structure is typical of steroid hormones, which are characterized by their four-ring carbon skeleton.

Pharmacology[edit | edit source]

Androstenediol 17-acetate acts as a prodrug for androstenediol. Once in the body, it is converted into androstenediol by the action of esterase enzymes. Androstenediol is a potent androgen, with effects similar to those of testosterone. It promotes the development of male secondary sexual characteristics and has anabolic effects on muscle and bone tissue.

Medical Uses[edit | edit source]

In the field of medicine, androstenediol 17-acetate is used for its androgenic and anabolic effects. It may be used in the treatment of conditions characterized by insufficient androgen production, such as hypogonadism. It may also be used to promote muscle growth in patients with wasting conditions, such as cancer or AIDS.

Side Effects[edit | edit source]

As with other androgens, androstenediol 17-acetate can have side effects. These may include acne, hair loss, and an increased risk of prostate cancer. It can also have masculinizing effects in women, such as deepening of the voice and growth of facial hair.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD