Benzhydrocodone

Benzhydrocodone.svg

Benzhydrocodone is a semisynthetic opioid analgesic used for the management of moderate to severe pain. It is a prodrug of hydrocodone, meaning it is metabolized in the body to produce the active drug hydrocodone. Benzhydrocodone is typically combined with acetaminophen in prescription medications to enhance its pain-relieving effects.

Pharmacology

Benzhydrocodone is designed to be less prone to abuse compared to hydrocodone. Upon ingestion, benzhydrocodone is converted into hydrocodone in the gastrointestinal tract. Hydrocodone then exerts its effects by binding to the mu-opioid receptors in the central nervous system, leading to analgesia, euphoria, and respiratory depression.

Medical Uses

Benzhydrocodone is prescribed for the relief of moderate to severe pain where the use of an opioid analgesic is appropriate. It is often used in cases where other pain management strategies are insufficient.

Side Effects

Common side effects of benzhydrocodone include:

• Nausea
• Vomiting
• Constipation
• Drowsiness
• Dizziness

Serious side effects may include:

• Respiratory depression
• Addiction
• Overdose

Contraindications

Benzhydrocodone should not be used in patients with:

• Severe respiratory depression
• Acute or severe bronchial asthma
• Known or suspected gastrointestinal obstruction, including paralytic ileus

Regulation

Benzhydrocodone is classified as a Schedule II controlled substance under the Controlled Substances Act in the United States, indicating it has a high potential for abuse which may lead to severe psychological or physical dependence.

See Also

• Opioid
• Hydrocodone
• Pain management
• Analgesic