Bromism

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Bromism
An introduction to dermatology (1905) Bromide Rash.jpg
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Headache, lethargy, tremor, slurred speech, ataxia, delirium, psychosis, skin rash
Complications Seizures, coma
Onset Gradual, with chronic exposure
Duration Variable, depending on exposure
Types N/A
Causes Excessive intake of bromide compounds
Risks Use of bromide-containing medications or substances
Diagnosis Clinical evaluation, serum bromide level
Differential diagnosis Other causes of altered mental status, other causes of skin rash
Prevention Avoidance of bromide compounds
Treatment Discontinuation of bromide exposure, supportive care, saline diuresis
Medication N/A
Prognosis Generally good with cessation of exposure
Frequency Rare in modern times
Deaths N/A


Bromism is a condition that occurs as a result of the excessive intake of bromide. Bromide is a chemical compound that was once widely used in medicine, particularly as a sedative and anticonvulsant. However, its use has declined significantly due to the risk of bromism and the development of more effective and safer medications.

Causes[edit | edit source]

Bromism is typically caused by the chronic ingestion of bromide-containing products. These can include certain types of medications, fire retardants, and even some types of food and drink. The condition can also occur as a result of occupational exposure to bromide.

Symptoms[edit | edit source]

The symptoms of bromism can vary widely, but often include neurological symptoms such as headache, fatigue, confusion, and hallucinations. Other symptoms can include gastrointestinal problems, skin rash, and cardiac abnormalities.

Diagnosis[edit | edit source]

Bromism is diagnosed based on the patient's history of exposure to bromide and the presence of characteristic symptoms. Laboratory tests can also be used to measure the level of bromide in the body.

Treatment[edit | edit source]

The primary treatment for bromism is to discontinue exposure to bromide. In severe cases, hemodialysis may be used to remove bromide from the body. Treatment also typically includes supportive care to manage symptoms.

Prevention[edit | edit source]

Prevention of bromism involves avoiding unnecessary exposure to bromide. This can include careful use of bromide-containing medications and avoiding occupational exposure to bromide.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD