Chlormadinone caproate

Chlormadinone caproate is a progestin medication which is used in hormone therapy. It is a derivative of progesterone and was first introduced in the 1960s. Chlormadinone caproate is not available in the United States but is used in other countries, primarily in Europe.

Pharmacology

Chlormadinone caproate is a progestogen, specifically a progestin, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It has strong progestogenic effects and weak antiandrogen and glucocorticoid effects.

Medical uses

Chlormadinone caproate is used in hormone therapy for the treatment of menopausal symptoms, gynecological disorders, and in combination with estrogen as a component of menopausal hormone therapy for the treatment of menopausal symptoms. It is also used as a form of birth control in combination with ethinylestradiol.

Side effects

Side effects of chlormadinone caproate include menstrual irregularities, headache, nausea, breast tenderness, and others.

See also

• List of progestogens
• List of progestogen esters

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