Chlorphenoxamine
An article about the antihistamine drug Chlorphenoxamine
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Chlorphenoxamine is a medication that belongs to the class of antihistamines. It is primarily used to treat allergic reactions and symptoms such as itching, runny nose, and sneezing.
Pharmacology[edit | edit source]
Chlorphenoxamine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It is a first-generation antihistamine, which means it can cross the blood-brain barrier and may cause sedation.
Uses[edit | edit source]
Chlorphenoxamine is used to relieve symptoms associated with allergic rhinitis, urticaria, and other allergic conditions. It may also be used as an adjunct in the treatment of anaphylaxis and angioedema.
Side Effects[edit | edit source]
Common side effects of chlorphenoxamine include drowsiness, dry mouth, and dizziness. Less common side effects may include blurred vision, constipation, and urinary retention.
Mechanism of Action[edit | edit source]
Chlorphenoxamine acts as an H1 receptor antagonist, preventing histamine from binding to its receptors and thereby reducing the symptoms of an allergic reaction. It also has mild anticholinergic properties, which contribute to its side effect profile.
History[edit | edit source]
Chlorphenoxamine was developed in the mid-20th century and has been used in various formulations for the treatment of allergic conditions. It is less commonly used today due to the availability of newer antihistamines with fewer side effects.
Related pages[edit | edit source]
Chlorphenoxamine
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