Combined immunodeficiencies
Combined Immunodeficiencies (CID) are a group of immune system disorders that are characterized by recurrent and severe infections, often from a very young age. These conditions are caused by defects in the immune system that affect the functioning of both the T cells and B cells.
Overview[edit | edit source]
Combined immunodeficiencies are a group of disorders that primarily affect the immune system. These disorders are characterized by increased susceptibility to infections, particularly those caused by bacteria, viruses, and fungi. The immune system is composed of various types of cells that work together to defend the body against harmful substances. In people with combined immunodeficiencies, the immune system is not able to function properly, leading to recurrent and severe infections.
Causes[edit | edit source]
Combined immunodeficiencies are usually caused by genetic mutations that affect the development or function of the immune system. These mutations can be inherited from parents or can occur spontaneously during the development of the immune system.
Symptoms[edit | edit source]
The symptoms of combined immunodeficiencies can vary widely, but they often include recurrent infections, growth delays, and an increased risk of developing autoimmune disorders or cancers. The severity of the symptoms can also vary, with some people experiencing mild symptoms and others experiencing severe and life-threatening complications.
Diagnosis[edit | edit source]
The diagnosis of combined immunodeficiencies is usually based on a combination of clinical findings, laboratory tests, and genetic testing. Laboratory tests can help to identify abnormalities in the immune system, while genetic testing can help to identify the specific mutation that is causing the disorder.
Treatment[edit | edit source]
The treatment of combined immunodeficiencies is usually aimed at managing the symptoms and preventing complications. This can include antibiotics to treat infections, immunoglobulin therapy to boost the immune system, and in some cases, bone marrow transplantation to replace the defective immune system.
See Also[edit | edit source]
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