Denaverine
Denaverine is a vasodilator and antispasmodic drug that is used in the treatment of conditions such as angina pectoris and peripheral vascular disease. It is a derivative of papaverine, a non-narcotic alkaloid extracted from the opium poppy, Papaver somniferum.
Etymology[edit | edit source]
The term "Denaverine" is derived from the Latin word "dena", meaning "ten", and "verine", a suffix used in the names of various drugs. The "ten" in the name may refer to the fact that denaverine is a derivative of papaverine, which is itself derived from the opium poppy, a plant that has been used for medicinal purposes for thousands of years.
Pharmacology[edit | edit source]
Denaverine acts as a phosphodiesterase inhibitor, which means it blocks the action of an enzyme called phosphodiesterase. This enzyme is involved in the breakdown of a substance called cyclic adenosine monophosphate (cAMP), which plays a key role in the relaxation of smooth muscle tissue. By inhibiting the action of phosphodiesterase, denaverine helps to increase the levels of cAMP in the body, leading to relaxation of smooth muscle tissue and dilation of blood vessels.
Medical Uses[edit | edit source]
Denaverine is used in the treatment of conditions such as angina pectoris and peripheral vascular disease. Angina pectoris is a condition characterized by chest pain due to reduced blood flow to the heart, while peripheral vascular disease is a condition characterized by narrowed blood vessels and reduced blood flow to the limbs. By dilating the blood vessels, denaverine helps to improve blood flow and alleviate the symptoms of these conditions.
Side Effects[edit | edit source]
Like all drugs, denaverine can cause side effects. These may include headache, dizziness, flushing, and gastrointestinal disturbances. In rare cases, denaverine may cause serious side effects such as arrhythmias (irregular heartbeats) and hypotension (low blood pressure).
Related Terms[edit | edit source]
- Vasodilator
- Antispasmodic
- Angina pectoris
- Peripheral vascular disease
- Papaverine
- Phosphodiesterase inhibitor
| Denaverine Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
