Dextronorgestrel

Dextronorgestrel is a synthetic hormone used in a variety of contraceptive methods. It is a type of progestin, which is a group of hormones that play an important role in the female reproductive system. Dextronorgestrel is used in many different forms of contraception including intrauterine devices (IUDs), contraceptive implants, and birth control pills.

Mechanism of Action

Dextronorgestrel works primarily by preventing ovulation. It does this by suppressing the release of gonadotropins, which are hormones that stimulate the ovaries to release eggs. In addition to preventing ovulation, dextronorgestrel also thickens the cervical mucus, making it more difficult for sperm to reach the egg. It also thins the lining of the uterus, making it less likely that a fertilized egg will be able to implant and develop.

Uses

Dextronorgestrel is used in a variety of contraceptive methods. These include:

• Intrauterine devices (IUDs): The Mirena and Skyla IUDs both release small amounts of dextronorgestrel directly into the uterus. This provides highly effective contraception that can last for several years.

• Contraceptive implants: The Nexplanon implant is a small rod that is inserted under the skin of the upper arm. It releases dextronorgestrel continuously, providing effective contraception for up to three years.

• Birth control pills: Some types of birth control pills contain dextronorgestrel in combination with an estrogen. These pills are taken daily to prevent pregnancy.

Side Effects

Like all medications, dextronorgestrel can cause side effects. These can include nausea, headache, breast tenderness, and changes in menstrual bleeding patterns. In rare cases, serious side effects can occur, including blood clots, stroke, and heart attack.

See Also

• Contraception
• Progestin
• Intrauterine device
• Birth control pill