Diethylpropion hydrochloride

Diethylpropion hydrochloride is a pharmaceutical drug used primarily in the treatment of obesity. It is a sympathomimetic amine, which is similar to an amphetamine. It is also known as a "anorectic" or "anorexigenic" drug. Diethylpropion hydrochloride stimulates the central nervous system (nerves and brain), which increases your heart rate and blood pressure and decreases your appetite.

Pharmacology

Diethylpropion hydrochloride is a norepinephrine releasing agent. It works by stimulating the release of chemicals in the brain that suppress appetite. The drug is metabolized extensively through a complex pathway of biotransformation involving simple organic acids and peptides.

Medical uses

Diethylpropion hydrochloride is used as a short-term supplement to diet and exercise in the treatment of obesity. It is also used in some cases for the management of exogenous obesity as a short term adjunct in a regimen of weight reduction based on caloric restriction.

Side effects

Common side effects of diethylpropion hydrochloride include restlessness, nervousness, difficulty sleeping, or dry mouth. Serious side effects can include increased blood pressure, heart palpitations, shortness of breath, swelling of the legs and ankles, chest pain, and trouble doing activities you've been able to do.

Contraindications

Diethylpropion hydrochloride is contraindicated in patients with cardiovascular disease, severe hypertension, hyperthyroidism, glaucoma, history of drug abuse, hypersensitivity to sympathomimetic amines, and in patients who are currently taking or have taken monoamine oxidase inhibitors within the preceding 14 days.

See also

• Phentermine
• Amfepramone
• Cathine
• Cathinone
• Methcathinone
• Ephedrine
• Pseudoephedrine
• Phenethylamine
• Amphetamine
• Methamphetamine