Dorastine
An overview of the medication Dorastine
Dorastine is a pharmaceutical drug used primarily for the treatment of allergic reactions and inflammatory conditions. It belongs to the class of antihistamines, which are medications that counteract the effects of histamine, a chemical involved in allergic responses.
Mechanism of Action[edit | edit source]
Dorastine works by blocking the H1 histamine receptors in the body. Histamine is a substance that is released by the immune system during an allergic reaction, leading to symptoms such as itching, swelling, and redness. By preventing histamine from binding to its receptors, Dorastine reduces these symptoms.
Indications[edit | edit source]
Dorastine is indicated for the treatment of:
Dosage and Administration[edit | edit source]
Dorastine is typically administered orally in the form of tablets or liquid suspension. The dosage depends on the age, weight, and medical condition of the patient. It is important to follow the prescribing physician's instructions and not to exceed the recommended dose.
Side Effects[edit | edit source]
Common side effects of Dorastine may include:
Less common but more serious side effects can include:
Contraindications[edit | edit source]
Dorastine should not be used in patients with:
- Known hypersensitivity to Dorastine or any of its components
- Severe liver disease
Drug Interactions[edit | edit source]
Dorastine may interact with other medications, such as:
Pharmacokinetics[edit | edit source]
Dorastine is well absorbed from the gastrointestinal tract, with peak plasma concentrations occurring within 1 to 2 hours after oral administration. It is metabolized in the liver and excreted primarily in the urine.
Research and Development[edit | edit source]
Ongoing research is exploring the potential of Dorastine in treating other conditions, such as chronic urticaria and atopic dermatitis.
Also see[edit | edit source]
First Generation Antihistamines
- Brompheniramine
- Carbinoxamine
- Chlorcyclizine
- Chlorpheniramine
- Clemastine
- Cyclizine
- Cyproheptadine
- Dexbrompheniramine
- Dexchlorpheniramine
- Dimenhydrinate
- Diphenhydramine
- Doxylamine
- Hydroxyzine
- Meclizine
- Phenyltoloxamine
- Promethazine
- Triprolidine
Second Generation Antihistamines
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