Estrone acetate

Estrone acetate is a steroid and estrogen that is used in hormone therapy. It is an acetate ester of estrone, which is one of the three main naturally occurring estrogens, the others being estradiol and estriol.

Pharmacology

Estrone acetate is a prodrug of estrone, meaning it is metabolized in the body to produce estrone. Estrone is a weak estrogen, meaning it has less effect on the body than other forms of estrogen like estradiol. However, it is still important in the body, particularly in postmenopausal women, where it is the main form of estrogen produced.

Medical uses

Estrone acetate is used in hormone therapy for menopausal symptoms and osteoporosis. It can also be used in the treatment of estrogen-dependent conditions such as breast cancer and prostate cancer.

Side effects

Like all estrogens, estrone acetate can have a number of side effects. These can include nausea, bloating, breast tenderness, and an increased risk of blood clots and stroke. It can also increase the risk of certain types of cancer, including endometrial cancer and breast cancer.

See also

• List of estrogens
• List of steroid esters
• List of hormonal cytostatic antineoplastic agents

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