Estrone cyanate

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Estrone cyanate


Estrone cyanate is a synthetic, steroidal estrogen that is no longer marketed. It is an estrogen ester and a cyanate ester – specifically, the 3-cyanate ester of estrone. Estrone cyanate was first described in the literature in 1939 and was introduced for medical use by 1940.

Chemistry[edit | edit source]

Estrone cyanate, also known as estrone 3-cyanate, as well as estra-1,3,5(10)-trien-17-one 3-cyanate, is a synthetic estrane steroid and a derivative of estrone. It is an estrogen ester, specifically the 3-cyanate ester of estrone. Other estrone esters include estrone acetate, estrone sulfate, and estrone phosphate.

History[edit | edit source]

Estrone cyanate was first described in the literature in 1939. It was introduced for medical use by 1940. However, it is no longer marketed.

Society and culture[edit | edit source]

Estrone cyanate was marketed under the brand name Gynocyrol. It is no longer available.

See also[edit | edit source]

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Contributors: Prab R. Tumpati, MD