Ethylone

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Bk-MDEA

Ethylone is a synthetic compound that belongs to the substituted cathinone family, which is a group of compounds derived from the khat plant. It is chemically similar to other synthetic cathinones like mephedrone and methylone, and it is often found in products sold as bath salts or research chemicals. Ethylone is known for its stimulant and entactogenic effects, which are similar to those of MDMA, but it is considered to be less potent.

Chemistry[edit | edit source]

Ethylone, also known as 3,4-methylenedioxy-N-ethylcathinone (MDEC) or βk-MDEA, is a synthetic molecule of the cathinone family. The chemical formula for Ethylone is C12H15NO3. It features a phenethylamine core with an alkyl group attached to the alpha carbon and an oxygen group attached to the beta carbon. Additionally, it has a methylenedioxy group attached to the benzene ring. This structure is what classifies it as a substituted cathinone.

Pharmacology[edit | edit source]

The pharmacological action of Ethylone is primarily due to its function as a monoamine releasing agent. It is believed to increase the levels of serotonin, dopamine, and norepinephrine in the brain by inhibiting their reuptake. This action results in stimulating and euphoric effects. However, the exact mechanism of action of Ethylone and its full pharmacological profile is not well understood due to the lack of scientific research on this substance.

Effects[edit | edit source]

Users of Ethylone report a range of subjective effects that are similar to other stimulants and entactogens. These effects can include feelings of euphoria, increased sociability, mental and physical stimulation, enhanced sensory perception, and empathy. However, adverse effects are also reported, which can include anxiety, paranoia, nausea, and increased heart rate and blood pressure. The effects of Ethylone can vary greatly depending on the dose, the individual's physiology, and the presence of other substances.

Legality[edit | edit source]

The legal status of Ethylone varies from country to country. In many jurisdictions, it is a controlled substance due to its potential for abuse and the health risks associated with its use. For example, in the United States, Ethylone is classified as a Schedule I controlled substance under the Federal Analog Act, as it is structurally similar to MDMA, which is a Schedule I substance. Other countries have similar laws that prohibit the manufacture, distribution, and possession of Ethylone.

Safety[edit | edit source]

As with other synthetic cathinones, there is limited information on the safety profile of Ethylone. Its use can be associated with significant health risks, including the potential for abuse, addiction, and various negative physical and psychological effects. Due to its legal status and the risks associated with its use, it is strongly recommended to avoid non-medical use of Ethylone.

Conclusion[edit | edit source]

Ethylone is a synthetic cathinone with stimulant and entactogenic properties. While it shares similarities with other compounds in its class, the lack of research on its effects and safety profile makes it a substance of concern. Its legal status as a controlled substance in many countries reflects the potential risks associated with its use.


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Contributors: Prab R. Tumpati, MD