Exorphin

From WikiMD's Wellness Encyclopedia


Exorphins are a type of peptide with opioid activity that are formed during the digestion of certain foods. These peptides are similar in structure and function to endorphins, which are naturally produced by the body. Exorphins can bind to opioid receptors in the brain, potentially influencing mood, pain perception, and behavior.

Types of Exorphins[edit | edit source]

Exorphins are typically derived from the digestion of gluten and casein, which are proteins found in wheat and dairy products, respectively. The most well-known exorphins include:

  • Gliadorphin: Derived from the digestion of gluten.
  • Casomorphin: Derived from the digestion of casein.

Mechanism of Action[edit | edit source]

Exorphins exert their effects by binding to opioid receptors, which are part of the endogenous opioid system. This system is involved in regulating pain, reward, and addictive behaviors. By mimicking the action of endorphins, exorphins can influence these physiological processes.

Potential Health Implications[edit | edit source]

The presence of exorphins in the diet has been hypothesized to contribute to various health conditions, including:

However, the exact role of exorphins in these conditions remains a topic of ongoing research and debate.

Related Pages[edit | edit source]

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD