Fat necrosis

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Fat necrosis
Synonyms also known as Balser's necrosis
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Fat necrosis is a form of necrosis characterized by the action upon fat by digestive enzymes.[1]

In fat necrosis the enzyme lipase releases fatty acids from triglycerides. The fatty acids then complex with calcium to form soaps. These soaps appear as white chalky deposits.[2]

It is usually associated with trauma of the pancreas or acute pancreatitis.[2][3]

It can also occur in the breast,[4] the salivary glands[5] and neonates after a traumatic delivery.

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References[edit | edit source]

  1. Cell Injury Full text, ,
  2. 2.0 2.1 Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007). Robbins Basic Pathology (8th ed.). Saunders Elsevier. pp. 10-11 ISBN 978-1-4160-2973-1
  3. "fat necrosis" at Dorland's Medical Dictionary
  4. , Fat necrosis after partial-breast irradiation with brachytherapy or electron irradiation versus standard whole-breast radiotherapy--4-year results of a randomized trial, Int. J. Radiat. Oncol. Biol. Phys., Vol. 69(Issue: 3), pp. 724–31, DOI: 10.1016/j.ijrobp.2007.03.055, PMID: 17524571,
  5. Archived copy Full text, , Accessed on: 2011-09-19.


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