Fat necrosis

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Fat necrosis is a form of necrosis characterized by the action upon fat by digestive enzymes.[1]

In fat necrosis the enzyme lipase releases fatty acids from triglycerides. The fatty acids then complex with calcium to form soaps. These soaps appear as white chalky deposits.[2]

It is usually associated with trauma of the pancreas or acute pancreatitis.[2][3]

It can also occur in the breast,[4] the salivary glands[5] and neonates after a traumatic delivery.

See also[edit | edit source]

References[edit | edit source]

  1. "Cell Injury".
  2. 2.0 2.1 Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; & Mitchell, Richard N. (2007). Robbins Basic Pathology (8th ed.). Saunders Elsevier. pp. 10-11 ISBN 978-1-4160-2973-1
  3. "fat necrosis" at Dorland's Medical Dictionary
  4. "Archived copy". Archived from the original on 2011-04-14. Retrieved 2011-09-19. {{cite web}}: Unknown parameter |dead-url= ignored (help)CS1 maint: archived copy as title (link)


External links[edit | edit source]

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Contributors: Prab R. Tumpati, MD