Fibroepithelial neoplasms

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Fibroepithelial neoplasms are a group of tumors that are composed of both epithelial cells and fibroblasts. These tumors can occur in various parts of the body, but are most commonly found in the skin and mucous membranes. They can be benign or malignant, and their behavior can vary widely depending on the specific type of tumor and its location.

Types of Fibroepithelial Neoplasms[edit | edit source]

There are several types of fibroepithelial neoplasms, including:

  • Fibroadenoma: This is a benign tumor that most commonly occurs in the breast. It is composed of both glandular and stromal tissue.
  • Phyllodes tumor: This is a rare breast tumor that can be benign, borderline, or malignant. It is characterized by leaf-like projections of stromal cells.
  • Dermatofibroma: Also known as a fibrous histiocytoma, this is a common benign skin tumor that is composed of fibroblasts and histiocytes.
  • Dermatofibrosarcoma protuberans: This is a rare type of skin cancer that is composed of fibroblasts. It is characterized by its slow growth and tendency to recur after removal.

Diagnosis and Treatment[edit | edit source]

The diagnosis of fibroepithelial neoplasms typically involves a combination of physical examination, imaging studies, and biopsy. The specific tests used will depend on the suspected type of tumor and its location.

Treatment for fibroepithelial neoplasms varies depending on the type of tumor, its size and location, and whether it is benign or malignant. Treatment options may include surgery, radiation therapy, and/or chemotherapy.

Prognosis[edit | edit source]

The prognosis for individuals with fibroepithelial neoplasms depends on several factors, including the type of tumor, its size and location, and whether it is benign or malignant. In general, benign tumors have a good prognosis, while malignant tumors can be more challenging to treat and may have a poorer prognosis.

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Contributors: Prab R. Tumpati, MD