Fos
Fos - retrovirus-associated dna sequences (fos) originally isolated from the finkel-biskis-jinkins (fbj-msv) and finkel-biskis-reilly (fbr-msv) murine sarcoma viruses. The proto-oncogene c-fos encodes a nuclear protein that dimerizes with jun via a zipper motif to form the transcription factor ap1 and is involved in growth-related transcriptional control. The insertion of c-fos into fbj-msv or fbr-msv induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-3 on the long arm of chromosome 14.
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