Glassy cell carcinoma of the cervix
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Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour of the uterine cervix.[1] The tumour gets its name from its microscopic appearance; its cytoplasm has a glass-like appearance.
Signs and symptoms[edit | edit source]
The signs and symptoms are similar to other cervical cancers and may include post-coital bleeding and/or pain during intercourse (dyspareunia). Early lesions may be completely asymptomatic.
Cause[edit | edit source]
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Diagnosis[edit | edit source]
The diagnosis is based on tissue examination, e.g. biopsy.
Under the microscope, glassy cell carcinoma tumours are composed of cells with a glass-like cytoplasm, typically associated with an inflammatory infiltrate abundant in eosinophils and very mitotically active. PAS staining highlights the plasma membrane.[2]
Treatment[edit | edit source]
The treatment is dependent on the stage. Advanced tumours are treated with surgery (radical hysterectomy and bilateral salpingo-opherectomy), radiation therapy and chemotherapy.[2]
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