HCT-116

HCT-116 is a cell line derived from human colorectal carcinoma. It is often used in biological research and drug development due to its high genetic stability and the presence of specific gene mutations that are characteristic of many types of cancer.

History

The HCT-116 cell line was first established in 1968 from a 44-year-old male patient with colorectal carcinoma. Since then, it has been widely used in various fields of research, including oncology, genetics, pharmacology, and cell biology.

Characteristics

HCT-116 cells are characterized by their high genetic stability, which makes them an ideal model for studying the effects of various drug compounds on cancer cells. They also possess specific gene mutations, such as in the KRAS and PIK3CA genes, which are commonly found in many types of cancer.

Applications

Due to their unique characteristics, HCT-116 cells are widely used in the development and testing of new cancer therapies. They are also used in studies investigating the mechanisms of cancer progression and metastasis, as well as in the identification of potential biomarkers for cancer diagnosis and prognosis.

See also

• Cell culture
• Cancer research
• Drug development

References

‎

---

Translate: - East Asian 中文, 日本, 한국어, South Asian हिन्दी, தமிழ், తెలుగు, Urdu, ಕನ್ನಡ, Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, বাংলা
European español, Deutsch, français, Greek, português do Brasil, polski, română, русский, Nederlands, norsk, svenska, suomi, Italian
Middle Eastern & African عربى, Turkish, Persian, Hebrew, Afrikaans, isiZulu, Kiswahili,
Other Bulgarian, Hungarian, Czech, Swedish, മലയാളം, मराठी, ਪੰਜਾਬੀ, ગુજરાતી, Portuguese, Ukrainian