HCT-116
HCT-116 is a cell line derived from human colorectal carcinoma. It is often used in biological research and drug development due to its high genetic stability and the presence of specific gene mutations that are characteristic of many types of cancer.
History[edit | edit source]
The HCT-116 cell line was first established in 1968 from a 44-year-old male patient with colorectal carcinoma. Since then, it has been widely used in various fields of research, including oncology, genetics, pharmacology, and cell biology.
Characteristics[edit | edit source]
HCT-116 cells are characterized by their high genetic stability, which makes them an ideal model for studying the effects of various drug compounds on cancer cells. They also possess specific gene mutations, such as in the KRAS and PIK3CA genes, which are commonly found in many types of cancer.
Applications[edit | edit source]
Due to their unique characteristics, HCT-116 cells are widely used in the development and testing of new cancer therapies. They are also used in studies investigating the mechanisms of cancer progression and metastasis, as well as in the identification of potential biomarkers for cancer diagnosis and prognosis.
See also[edit | edit source]
References[edit | edit source]
 | This medical article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
