Fludroxycortide

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Fludroxycortide is a synthetic corticosteroid used in the treatment of various skin conditions. It is known for its anti-inflammatory and immunosuppressive properties. Fludroxycortide is commonly applied topically to reduce inflammation and alleviate symptoms associated with dermatological disorders.

Medical Uses[edit | edit source]

Fludroxycortide is primarily used to treat inflammatory skin conditions such as eczema, psoriasis, and dermatitis. It helps to reduce redness, itching, and swelling by suppressing the immune response in the affected area. The medication is available in various forms, including cream, ointment, and gel.

Mechanism of Action[edit | edit source]

As a corticosteroid, fludroxycortide works by inhibiting the release of substances in the body that cause inflammation. It binds to glucocorticoid receptors in the skin cells, leading to a decrease in the production of inflammatory mediators such as prostaglandins and leukotrienes. This action helps to reduce the symptoms of inflammatory skin conditions.

Side Effects[edit | edit source]

Common side effects of fludroxycortide include skin irritation, dryness, and burning sensation at the application site. Prolonged use of corticosteroids can lead to more serious side effects such as skin thinning, striae, and telangiectasia. It is important to use this medication as directed by a healthcare professional to minimize the risk of adverse effects.

Precautions[edit | edit source]

Patients using fludroxycortide should avoid applying it to broken or infected skin. It is also important to avoid prolonged use, especially on large areas of the body, to prevent systemic absorption and potential side effects. Patients should inform their healthcare provider of any other medications they are taking and any pre-existing health conditions.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD