Haemophilia A

From WikiMD's Wellness Encyclopedia

Haemophilia A is a genetic disorder that affects the body's ability to clot blood. It is caused by a deficiency in factor VIII, a protein that is necessary for blood clotting. This condition is typically inherited and affects males more often than females.

Symptoms[edit | edit source]

The primary symptom of Haemophilia A is prolonged bleeding. This can occur after an injury or surgery, and in severe cases, spontaneous bleeding can occur. Other symptoms can include:

Causes[edit | edit source]

Haemophilia A is caused by a mutation in the F8 gene, which provides instructions for making factor VIII. This mutation can be inherited from a parent, or it can occur spontaneously.

Diagnosis[edit | edit source]

Diagnosis of Haemophilia A typically involves blood tests to measure the level of factor VIII in the blood. Genetic testing may also be used to identify the specific mutation causing the condition.

Treatment[edit | edit source]

Treatment for Haemophilia A typically involves replacing the missing factor VIII through infusions. Other treatments can include:

See Also[edit | edit source]

References[edit | edit source]


Haemophilia A Resources

Contributors: Prab R. Tumpati, MD