Hereditary papillary renal cancer
(heh-REH-dih-tayr-ee PA-pih-LAYR-ee REE-nul KAN-ser) is a rare, inherited disorder that increases the risk of a type of kidney cancer called type 1 papillary kidney cancer. This cancer forms in cells that line the small tubes in the kidney that filter waste from the blood and make urine. Hereditary papillary renal cancer often affects both kidneys, and often there is more than one tumor in each kidney. It is caused by mutations (changes) in a gene called MET. Hereditary papillary renal cancer is a type of hereditary cancer syndrome. Also called hereditary papillary renal carcinoma and HPRC.
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Contributors: Prab R. Tumpati, MD
