Hydroxydione

Hydroxydione is a steroid that was previously used as a sedative and anesthetic. It is a derivative of progesterone, a type of hormone that plays a role in the menstrual cycle and pregnancy. Hydroxydione was developed in the 1950s and was used in medicine for a short period of time before being discontinued due to its side effects.

History

Hydroxydione was first synthesized in the 1950s by the pharmaceutical company Hoffmann-La Roche. It was marketed under the brand name Perhydroxyl for use as a sedative and anesthetic. However, it was soon discontinued due to its side effects, which included nausea, vomiting, and dizziness.

Pharmacology

As a derivative of progesterone, hydroxydione has progestogenic effects. It works by binding to and activating the progesterone receptor, which in turn influences various bodily functions, including the menstrual cycle and pregnancy.

Side Effects

The side effects of hydroxydione include nausea, vomiting, and dizziness. These side effects led to its discontinuation in the medical field.

See Also

• Progesterone
• Sedative
• Anesthetic

Hydroxydione Resources
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