IgG4-related ophthalmic disease

From WikiMD's Wellness Encyclopedia

IgG4-related ophthalmic disease is a type of IgG4-related disease that affects the eyes and surrounding tissues. It is characterized by the infiltration of IgG4-positive plasma cells and lymphocytes into various organs, including the eye, lacrimal gland, and orbit. This disease can cause a variety of symptoms, including eye pain, swelling, and vision loss.

Symptoms[edit | edit source]

The symptoms of IgG4-related ophthalmic disease can vary widely, depending on the specific tissues affected. Common symptoms include:

Causes[edit | edit source]

The exact cause of IgG4-related ophthalmic disease is unknown. However, it is thought to be an autoimmune disease, in which the body's immune system mistakenly attacks its own tissues.

Diagnosis[edit | edit source]

Diagnosis of IgG4-related ophthalmic disease is often challenging due to its nonspecific symptoms and overlap with other diseases. It typically involves a combination of clinical evaluation, imaging studies, and tissue biopsy.

Treatment[edit | edit source]

Treatment for IgG4-related ophthalmic disease typically involves corticosteroids to reduce inflammation and suppress the immune response. In severe cases, other immunosuppressive drugs may be used.

See also[edit | edit source]

References[edit | edit source]


IgG4-related ophthalmic disease Resources
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Contributors: Prab R. Tumpati, MD