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Inamrinone lactate is a type of drug that belongs to the class of medications known as phosphodiesterase inhibitors. It is primarily used in the treatment of congestive heart failure and other cardiovascular diseases.

Pharmacology

Inamrinone lactate works by inhibiting the enzyme phosphodiesterase, which is responsible for breaking down cyclic adenosine monophosphate (cAMP) in the cells of the heart and blood vessels. By preventing the breakdown of cAMP, inamrinone lactate increases the force of the heart's contractions and widens the blood vessels. This reduces the amount of work the heart has to do to pump blood and increases the amount of blood that can flow through the blood vessels.

Clinical Use

Inamrinone lactate is used in the treatment of congestive heart failure, a condition in which the heart is unable to pump enough blood to meet the body's needs. It is typically used when other treatments have not been effective. Inamrinone lactate is administered intravenously in a hospital setting under the supervision of a healthcare professional.

Side Effects

Like all medications, inamrinone lactate can cause side effects. Common side effects include nausea, vomiting, diarrhea, and abdominal pain. More serious side effects can include arrhythmia (irregular heartbeat), hypotension (low blood pressure), and thrombocytopenia (low platelet count).

Contraindications

Inamrinone lactate should not be used in patients with known hypersensitivity to the drug. It should also be used with caution in patients with severe kidney disease, as the drug is primarily excreted by the kidneys.

See Also

• Phosphodiesterase inhibitors
• Congestive heart failure
• Cardiovascular diseases