Iproheptine

Iproheptine

Iproheptine is a pharmacological agent that belongs to the class of drugs known as antihistamines. It is primarily used in the treatment of allergic reactions, hay fever, and common cold symptoms.

Pharmacology

Iproheptine works by blocking the action of histamine, a substance in the body that causes allergic symptoms. It is a first-generation antihistamine, which means it can cross the blood-brain barrier and cause drowsiness. This makes it less suitable for daytime use compared to second-generation antihistamines, which are less likely to cause drowsiness.

Medical Uses

Iproheptine is used to relieve symptoms of the common cold and allergies, such as runny nose, sneezing, itchy or watery eyes, and itching of the nose or throat. It can also be used to treat urticaria (hives) and angioedema.

Side Effects

Common side effects of iproheptine include drowsiness, dizziness, dry mouth/nose/throat, constipation, blurred vision, and upset stomach. If these effects persist or worsen, medical attention should be sought. Serious side effects are rare, but can include mental/mood changes, difficulty urinating, or fast/irregular heartbeat.

Interactions

Iproheptine can interact with other medications, including antidepressants, sedatives, tranquilizers, and muscle relaxants, increasing their effects and potentially causing excessive drowsiness. It can also interact with MAO inhibitors, potentially leading to serious, possibly fatal, drug interactions.

Precautions

Before using iproheptine, patients should disclose their medical history, especially of breathing problems, glaucoma, heart problems, high blood pressure, liver disease, seizures, stomach problems, overactive thyroid, and difficulty urinating.

See Also

• Antihistamine
• Histamine
• Allergic reaction
• Hay fever
• Common cold