Iridogoniodysgenesis, dominant type

Autosomal dominant - en

Iridogoniodysgenesis, dominant type is a rare genetic disorder that affects the development of the iris and the anterior chamber of the eye. This condition is characterized by abnormalities in the iris and the trabecular meshwork, which can lead to glaucoma and other ocular complications.

Clinical Features

Individuals with iridogoniodysgenesis, dominant type, typically present with distinctive ocular features, including:

• Iris hypoplasia: Underdevelopment of the iris.
• Corectopia: Displacement of the pupil.
• Ectropion uveae: The presence of uveal tissue on the surface of the iris.
• Anterior segment dysgenesis: Abnormal development of the structures in the front part of the eye.

Genetics

Iridogoniodysgenesis, dominant type, is inherited in an autosomal dominant manner. This means that a single copy of the altered gene in each cell is sufficient to cause the disorder. The specific gene or genes involved in this condition are not yet fully understood, but it is known to be associated with mutations in genes that play a role in the development of the anterior chamber of the eye.

Diagnosis

The diagnosis of iridogoniodysgenesis, dominant type, is based on clinical examination and the identification of characteristic ocular features. Genetic testing may be used to confirm the diagnosis and to identify the specific genetic mutation responsible for the condition.

Management

Management of iridogoniodysgenesis, dominant type, focuses on monitoring and treating glaucoma and other ocular complications. This may include:

• Regular ophthalmologic examinations to monitor intraocular pressure and the health of the optic nerve.
• Medications to lower intraocular pressure.
• Surgical interventions, such as trabeculectomy or glaucoma drainage devices, to manage glaucoma.

Prognosis

The prognosis for individuals with iridogoniodysgenesis, dominant type, varies depending on the severity of the condition and the effectiveness of glaucoma management. Early diagnosis and appropriate treatment are crucial in preventing vision loss and other complications.

Related Pages

• Iris hypoplasia
• Corectopia
• Ectropion uveae
• Anterior segment dysgenesis
• Glaucoma
• Autosomal dominant
• Genetic testing
• Trabeculectomy
• Glaucoma drainage devices