Junctional epithelium

From WikiMD's Wellness Encyclopedia

Junctional epithelium is a specialized type of epithelium that connects the gingiva to the tooth surface. It plays a crucial role in maintaining the integrity of the periodontium and protecting the underlying connective tissue and alveolar bone from the microbial environment of the oral cavity.

Structure[edit | edit source]

The junctional epithelium is composed of two types of cells: basal cells and suprabasal cells. The basal cells are located at the base of the epithelium and are responsible for its renewal, while the suprabasal cells are located above the basal layer and are involved in the formation of the epithelial attachment to the tooth.

Function[edit | edit source]

The primary function of the junctional epithelium is to form a seal between the gingiva and the tooth, preventing the penetration of bacteria and other harmful substances into the underlying tissues. It also plays a role in the immune response to oral bacteria, as it contains immune cells such as neutrophils and lymphocytes that can respond to bacterial invasion.

Clinical significance[edit | edit source]

Alterations in the structure or function of the junctional epithelium can lead to periodontal diseases such as gingivitis and periodontitis. For example, the breakdown of the epithelial attachment can result in the formation of a periodontal pocket, which can harbor bacteria and exacerbate the inflammatory response.

See also[edit | edit source]

References[edit | edit source]





WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD