Lesopitron
Lesopitron is a selective serotonin receptor antagonist developed by Esteve. It is an anxiolytic drug of the azapirone class, similar to other azapirones like buspirone and ipsapirone.
Pharmacology[edit | edit source]
Lesopitron acts as a 5-HT1A receptor antagonist. The 5-HT1A receptor is a subtype of the 5-HT receptor that binds the neurotransmitter serotonin, and is prevalent in the cerebral cortex, hippocampus, septum, amygdala, and raphe nucleus, all of which are areas associated with anxiety and depression.
Clinical Use[edit | edit source]
Lesopitron is primarily used in the treatment of generalized anxiety disorder (GAD). It has been shown to have similar efficacy to benzodiazepines in treating GAD, but with fewer side effects such as sedation and dependency.
Side Effects[edit | edit source]
Common side effects of Lesopitron include dizziness, nausea, and headache. Less common side effects can include dry mouth, constipation, and changes in weight. As with all medications, it is important to monitor for any unusual or severe side effects and report them to a healthcare provider.
See Also[edit | edit source]
 | This pharmacology-related article is a stub. You can help WikiMD by expanding it. |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
