Lipoidal estradiol
Lipoidal estradiol is a lipid-soluble estrogen steroid that is used in hormone replacement therapy (HRT). It is a type of estradiol, which is the primary female sex hormone. Lipoidal estradiol is used to treat symptoms of menopause, such as hot flashes and vaginal dryness, and to prevent osteoporosis in postmenopausal women.
Pharmacology[edit | edit source]
Lipoidal estradiol is a prodrug of estradiol, meaning it is converted into estradiol in the body. It is more lipid-soluble than estradiol, which allows it to be absorbed more easily through the skin and mucous membranes. This makes it an effective ingredient in topical and transdermal estrogen products.
Uses[edit | edit source]
Lipoidal estradiol is used in HRT to replace the estrogen that the body no longer produces after menopause. It can help to alleviate menopausal symptoms and reduce the risk of developing osteoporosis. It may also be used in the treatment of certain types of breast cancer and prostate cancer.
Side Effects[edit | edit source]
Like all medications, lipoidal estradiol can cause side effects. These may include nausea, vomiting, bloating, breast tenderness, and headache. More serious side effects can include blood clots, stroke, and heart attack. It is important to discuss these risks with a healthcare provider before starting treatment.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD