Madelung's disease
Madelung's disease (also known as benign symmetric lipomatosis, Launois-Bensaude syndrome, or multiple symmetric lipomatosis) is a rare disorder characterized by the abnormal growth of fat deposits around the neck, shoulders, and upper arms. The disease is named after Otto Madelung, a German surgeon who first described the condition in the late 19th century.
Etiology[edit | edit source]
The exact cause of Madelung's disease is unknown, but it is believed to be related to alcoholism and genetic predisposition. The disease is more common in men than in women, and it usually appears between the ages of 30 and 60.
Symptoms[edit | edit source]
The most common symptom of Madelung's disease is the presence of multiple, symmetrical, non-painful fatty masses in the neck, shoulders, and upper arms. These masses can cause cosmetic concerns and may interfere with normal function. Other symptoms can include dyspnea (difficulty breathing), dysphagia (difficulty swallowing), and hoarseness.
Diagnosis[edit | edit source]
Diagnosis of Madelung's disease is typically based on the characteristic physical findings and can be confirmed by biopsy of the fatty masses. Imaging studies such as computed tomography (CT) or magnetic resonance imaging (MRI) can also be used to visualize the extent of the fat deposits.
Treatment[edit | edit source]
There is no cure for Madelung's disease, and treatment is primarily aimed at managing symptoms. This can include surgical removal of the fatty masses for cosmetic reasons or to improve function. In some cases, liposuction may be used.
Prognosis[edit | edit source]
The prognosis for individuals with Madelung's disease is generally good, although the disease can cause significant cosmetic and functional impairment. The disease does not typically affect life expectancy.
See also[edit | edit source]
NIH genetic and rare disease info[edit source]
Madelung's disease is a rare disease.
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