Moxisylyte

Moxisylyte

Moxisylyte is a vasodilator and alpha blocker used in the treatment of Raynaud's phenomenon and erectile dysfunction. It is marketed under the brand names Thymoxamine and Opilon.

Pharmacology

Moxisylyte is a selective alpha-1 adrenergic receptor antagonist. It works by blocking the action of norepinephrine on alpha-1 receptors, which leads to relaxation of smooth muscle in the arteries and arterioles. This results in an increase in blood flow and a decrease in blood pressure.

Medical uses

Moxisylyte is used in the treatment of Raynaud's phenomenon, a condition characterized by spasms of the small arteries of the fingers and toes, often in response to cold temperatures or stress. By blocking the action of norepinephrine on alpha-1 adrenergic receptors, Moxisylyte helps to prevent these spasms and increase blood flow to the affected areas.

In addition, Moxisylyte is also used in the treatment of erectile dysfunction. It works by relaxing the smooth muscle in the penis, which allows for increased blood flow and an erection to occur.

Side effects

Common side effects of Moxisylyte include headache, dizziness, nausea, and flushing. Less common side effects can include palpitations, tachycardia, and hypotension.

Contraindications

Moxisylyte is contraindicated in patients with a history of hypersensitivity to the drug, as well as in patients with severe hepatic impairment or severe renal impairment.

See also

• Alpha blocker
• Vasodilator
• Raynaud's phenomenon
• Erectile dysfunction