Pityriasis lichenoides et varioliformis acuta

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Pityriasis lichenoides et varioliformis acuta
Synonyms	PLEVA, Mucha-Habermann disease
Pronounce	N/A
Specialty	Dermatology
Symptoms	Rash, papules, vesicles, ulcers
Complications	Scarring, secondary infection
Onset	Sudden
Duration	Weeks to months
Types	N/A
Causes	Unknown, possibly immune system related
Risks	Infection, autoimmune disorders
Diagnosis	Clinical diagnosis, skin biopsy
Differential diagnosis	Chickenpox, smallpox, vasculitis
Prevention	N/A
Treatment	Antibiotics, corticosteroids, phototherapy
Medication	N/A
Prognosis	Generally good, may recur
Frequency	Rare
Deaths	N/A

Pityriasis Lichenoides et Varioliformis Acuta (PLEVA) is a rare skin disorder that is characterized by the sudden onset of small, red, scaling patches that can evolve into blisters or pustules. It is often abbreviated as PLEVA and is also known as Mucha-Habermann disease.

Symptoms

The symptoms of PLEVA include rashes, itching, and fevers. The rashes are usually small, red, and scaly, and they can evolve into blisters or pustules. The rashes can appear anywhere on the body, but they are most commonly found on the trunk, arms, and legs. The itching can be mild to severe, and it is often worse at night. The fevers are usually low-grade, but they can be higher if the disease is severe.

Causes

The exact cause of PLEVA is unknown, but it is thought to be an abnormal immune response to a viral or bacterial infection. Some researchers believe that it may be triggered by certain medications, such as antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.

Diagnosis

The diagnosis of PLEVA is usually based on the appearance of the skin lesions and the history of the symptoms. A skin biopsy may be performed to confirm the diagnosis. The biopsy usually shows a characteristic pattern of inflammation in the skin.

Treatment

The treatment of PLEVA is aimed at relieving the symptoms and preventing complications. This may include topical corticosteroids, antihistamines, and antibiotics. In severe cases, phototherapy or immunosuppressive drugs may be used.

Prognosis

The prognosis of PLEVA is generally good, but it can vary depending on the severity of the disease and the response to treatment. Most people with PLEVA recover completely within a few months, but some may have recurrent episodes.

See also

• Pityriasis lichenoides chronica
• Pityriasis rosea
• Pityriasis rubra pilaris