N,N-diethyltryptamine

N,N-Diethyltryptamine (DET) is a psychedelic drug belonging to the tryptamine family. It is historically known for its psychoactive properties and is classified as a Schedule I drug under the Controlled Substances Act in the United States.

Chemistry

N,N-Diethyltryptamine is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. DET is substituted at R2 of its indole heterocycle with an ethyl group.

Pharmacology

The pharmacology of N,N-Diethyltryptamine is similar to that of other tryptamines. It acts as a non-selective serotonin (5-HT) agonist, with a particular affinity for the 5-HT2A and 5-HT2C receptors. DET is thought to affect the human consciousness by altering the levels of serotonin in the brain, leading to altered mood and perception.

Effects

The effects of DET are highly dose-dependent and can vary greatly among individuals. At lower doses, effects can include feelings of euphoria, increased sensory awareness, and altered perception of time. At higher doses, these effects can become more intense and can include hallucinations, out-of-body experiences, and profound changes in thought and emotion.

Risks

As with all psychedelic substances, there are risks associated with the use of DET. These can include psychological distress, acute panic or anxiety, and potential harm to physical health. It is important for individuals to be aware of these risks and to use caution when considering the use of this substance.

Legal Status

In the United States, DET is classified as a Schedule I controlled substance, making it illegal to manufacture, buy, possess, or distribute without a license from the Drug Enforcement Administration (DEA).

See Also

• Tryptamine
• Psychedelic drug
• Controlled Substances Act

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