Neonatal sepsis

From WikiMD's Wellness Encyclopedia

Neonatal sepsis is a type of neonatal infection that occurs in an infant less than 28 days old. It is a systemic infection that can lead to serious complications and even death if not treated promptly and effectively.

Causes[edit | edit source]

Neonatal sepsis can be caused by a variety of bacteria, viruses, and fungi. The most common bacterial causes include Group B streptococcus, Escherichia coli, and Listeria monocytogenes. Viral causes can include herpes simplex virus and enterovirus, while fungal causes are typically due to Candida species.

Symptoms[edit | edit source]

Symptoms of neonatal sepsis can vary widely and may include fever, hypothermia, apnea, tachycardia, cyanosis, jaundice, and seizures. Infants may also exhibit feeding difficulties, lethargy, and irritability.

Diagnosis[edit | edit source]

Diagnosis of neonatal sepsis typically involves a combination of medical history, physical examination, and laboratory tests. These tests may include blood culture, complete blood count, C-reactive protein, and procalcitonin levels. Imaging studies such as chest X-ray or ultrasound may also be used.

Treatment[edit | edit source]

Treatment for neonatal sepsis typically involves antibiotic therapy, often with a combination of drugs to cover a broad range of potential pathogens. Supportive care, including intravenous fluids, oxygen therapy, and mechanical ventilation, may also be necessary.

Prevention[edit | edit source]

Prevention of neonatal sepsis can involve a variety of strategies, including infection control measures in the hospital, vaccination of pregnant women, and prophylactic antibiotic treatment for high-risk infants.

See also[edit | edit source]

Neonatal sepsis Resources
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Contributors: Prab R. Tumpati, MD