Nodular melanoma

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Nodular Melanoma is a type of melanoma that is typically characterized by its rapid growth and vertical invasion. It is the second most common subtype of melanoma, accounting for approximately 15-30% of all cases.

Overview[edit | edit source]

Nodular melanoma often presents as a firm, round or oval-shaped, darkly pigmented or occasionally amelanotic (lacking pigment) nodule. Unlike other types of melanoma, nodular melanoma tends to grow more vertically than horizontally, which can lead to a quicker invasion of the dermis and subcutaneous tissue. This rapid growth and invasion can make nodular melanoma more dangerous than other types of melanoma.

Symptoms[edit | edit source]

The most common symptom of nodular melanoma is a rapidly growing, darkly pigmented nodule. Other symptoms can include changes in the size, shape, or color of an existing mole, or the development of a new mole. The nodule may also be itchy or bleed.

Diagnosis[edit | edit source]

The diagnosis of nodular melanoma is typically made through a biopsy of the suspicious lesion. The biopsy is then examined under a microscope by a pathologist to confirm the diagnosis. Other diagnostic tests, such as imaging studies or a sentinel lymph node biopsy, may also be performed to determine the extent of the disease.

Treatment[edit | edit source]

The primary treatment for nodular melanoma is surgical removal of the tumor and a margin of normal tissue surrounding it. In some cases, additional treatments such as chemotherapy, immunotherapy, or radiation therapy may be recommended.

Prognosis[edit | edit source]

The prognosis for nodular melanoma depends on a number of factors, including the thickness of the tumor, the presence of ulceration, and whether the cancer has spread to the lymph nodes or other parts of the body.

See also[edit | edit source]

Nodular melanoma Resources
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Contributors: Prab R. Tumpati, MD