Nodular sclerosis

Nodular sclerosis is a subtype of Hodgkin's lymphoma characterized by the presence of large, abnormal cells known as Reed-Sternberg cells in the lymph nodes. It is the most common type of Hodgkin's lymphoma, accounting for approximately 60-80% of all cases.

Symptoms

The symptoms of nodular sclerosis can vary, but often include:

• Swollen lymph nodes in the neck, armpits, or groin
• Fever
• Night sweats
• Weight loss
• Fatigue
• Itchy skin

Diagnosis

The diagnosis of nodular sclerosis is typically made through a biopsy of an enlarged lymph node. The biopsy sample is examined under a microscope to look for the presence of Reed-Sternberg cells. Other tests, such as blood tests, imaging tests, and a bone marrow biopsy, may also be performed to determine the extent of the disease.

Treatment

The treatment for nodular sclerosis depends on the stage of the disease and the patient's overall health. Treatment options may include:

• Chemotherapy
• Radiation therapy
• Stem cell transplant
• Immunotherapy

Prognosis

The prognosis for nodular sclerosis is generally good, with many patients achieving long-term remission. However, the prognosis can vary depending on factors such as the stage of the disease at diagnosis and the patient's response to treatment.

See also

• Hodgkin's lymphoma
• Non-Hodgkin's lymphoma
• Lymphoma
• Cancer

Nodular sclerosis Resources
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