O-Toluidine

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Synonyms[edit source]

o-Toluidine, 2-Aminotoluene, 2-Methylaniline, 2-Methylbenzenamine, CI 37077, O-TOLUIDINE, o-Toluidine Hydrochloride, ortho-Toluidine

Thesaurus

A synthetic, light sensitive, light yellow liquid that is slightly soluble in water and miscible with carbon tetrachloride, diethyl ether and ethanol. The hydrochloride is a synthetic, light sensitive, white crystalline powder that is soluble in dimethylsulfoxide and ethanol. o-Toluidine and o-toluidine hydrochloride are used primarily as intermediates in the manufacture of dyes and pigments. When heated to decomposition, o-toluidine emits toxic fumes of nitrogen oxides while the hydrochloride also produces hydrochloric acid. Four studies of workers exposed to o-toluidine reported an excess of bladder cancers. o-Toluidine and o-toluidine hydrochloride are reasonably anticipated to be human carcinogens. (NCI05), Hazardous or Poisonous Substance

  • NCI Thesaurus (external)
C45178.

This concise article on O-Toluidine incorporates public domain text from the US National Library of Medicine.


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Contributors: Prab R. Tumpati, MD