Omnadren 250

From WikiMD's Wellness Encyclopedia

Omnadren 250 is a pharmaceutical drug used in androgen replacement therapy. It is a mixture of four different testosterone esters: testosterone propionate, testosterone phenylpropionate, testosterone isocaproate, and testosterone decanoate. This combination is designed to provide a rapid peak in testosterone levels followed by a more extended release, aiming to mimic the body's natural testosterone fluctuations more closely than single-ester preparations.

Composition[edit | edit source]

Omnadren 250 contains the following testosterone esters in specific proportions:

The total amount of testosterone per 1 ml of solution is 250 mg, hence the name Omnadren 250.

Indications[edit | edit source]

Omnadren 250 is primarily indicated for use in men with hypogonadism, a condition in which the body does not produce enough testosterone. Symptoms of hypogonadism can include reduced sexual desire, infertility, fatigue, depressed mood, and bone loss. By supplementing the body's natural testosterone, Omnadren 250 can help alleviate these symptoms.

Administration[edit | edit source]

Omnadren 250 is administered via intramuscular injection. The frequency of injections is typically once every three to four weeks, but the exact schedule can vary based on the individual's response to treatment and the advice of a healthcare provider.

Side Effects[edit | edit source]

As with any testosterone replacement therapy, Omnadren 250 can cause side effects. These may include:

  • Acne
  • Increased body hair
  • Mood swings
  • Changes in cholesterol levels
  • Increased red blood cell count, which can increase the risk of clotting
  • Infertility
  • Enlarged prostate

Patients are advised to discuss potential side effects with their healthcare provider before starting treatment.

Contraindications[edit | edit source]

Omnadren 250 should not be used in individuals with known hypersensitivity to testosterone or any of the esters contained in the medication. It is also contraindicated in patients with prostate cancer, as testosterone can stimulate the growth of prostate tumors.

Pharmacology[edit | edit source]

The pharmacokinetics of Omnadren 250 are characterized by a rapid increase in serum testosterone levels following administration, with a sustained release over time due to the different absorption rates of the esters. This profile aims to provide stable testosterone levels, reducing the peaks and troughs associated with some other forms of testosterone replacement therapy.

Comparison with Other Testosterone Preparations[edit | edit source]

Omnadren 250 is similar to other testosterone mixtures such as Sustanon 250, but the proportion and types of esters differ. These differences can affect the drug's release profile and the frequency of administration required to maintain stable testosterone levels.

Legal Status[edit | edit source]

The legal status of Omnadren 250 varies by country. In some jurisdictions, it is available by prescription only, while in others, it may be controlled more strictly due to potential for abuse and side effects.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD