Testosterone phenylpropionate
An overview of Testosterone phenylpropionate
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Testosterone phenylpropionate is an androgen and anabolic steroid (AAS) and a testosterone ester. It was formerly used in medicine but is now mostly used in veterinary medicine.
Pharmacology[edit | edit source]
Testosterone phenylpropionate is a synthetic androgen and anabolic steroid and an androgen ester; specifically, it is the C17β phenylpropionate (phenylpropanoate) ester of testosterone.
Mechanism of Action[edit | edit source]
As an androgen, testosterone phenylpropionate binds to the androgen receptor, activating it and leading to the expression of specific genes. This results in the development and maintenance of male secondary sexual characteristics and the promotion of muscle growth.
Pharmacokinetics[edit | edit source]
Testosterone phenylpropionate is administered via intramuscular injection. It has a relatively long half-life and duration of action due to the presence of the phenylpropionate ester, which slows the release of testosterone into the bloodstream.
Medical Uses[edit | edit source]
Testosterone phenylpropionate was used in the past for the treatment of male hypogonadism, andropause, and certain types of breast cancer in women. However, it has largely been replaced by other testosterone esters with more favorable pharmacokinetic profiles.
Side Effects[edit | edit source]
Common side effects of testosterone phenylpropionate include acne, oily skin, hair loss, and increased aggression. Long-term use can lead to cardiovascular disease, liver damage, and infertility.
History[edit | edit source]
Testosterone phenylpropionate was first synthesized in the 1950s and was used in clinical practice for several decades. It was marketed under various brand names, including Testolent and Testoviron.
Veterinary Use[edit | edit source]
In veterinary medicine, testosterone phenylpropionate is used to promote growth and improve feed efficiency in livestock.
Also see[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
