Testosterone decanoate
Testosterone decanoate is an androgen and anabolic steroid (AAS) medication which is used mainly in the treatment of low testosterone levels in men.[1] It is also used in hormone therapy for transgender men.[2] It is given by injection into muscle usually once every one to four weeks.[3]
Medical uses[edit | edit source]
Testosterone decanoate is used primarily in androgen replacement therapy. It is specifically used to treat hypogonadism in men, which results in low testosterone levels.[4] It is also used in hormone therapy for transgender men.[5]
Side effects[edit | edit source]
Side effects of testosterone decanoate include symptoms of masculinization like acne, increased hair growth, voice changes, and increased sexual desire.[6] The drug is a controlled substance, specifically a Schedule III controlled substance, which means it has a potential for abuse and dependence.[7]
Pharmacology[edit | edit source]
As an AAS, testosterone decanoate is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).[8] It has strong anabolic effects and weak androgenic effects, which give it a mild side effect profile and make it especially suitable for use in women.[9]
See also[edit | edit source]
References[edit | edit source]
- ↑ "Testosterone Decanoate - an overview". Retrieved 2021-09-30.
- ↑ "Testosterone therapy in transgender men". Retrieved 2021-09-30.
- ↑ "Testosterone Decanoate". Retrieved 2021-09-30.
- ↑ "Testosterone therapy in men with hypogonadism". Retrieved 2021-09-30.
- ↑ "Testosterone therapy in transgender men". Retrieved 2021-09-30.
- ↑ "Testosterone therapy: Potential benefits and risks as you age". Retrieved 2021-09-30.
- ↑ "Controlled Substances - Alphabetical Order" (PDF). Retrieved 2021-09-30.
- ↑ "Androgen receptor". Retrieved 2021-09-30.
- ↑ "Anabolic steroids". Retrieved 2021-09-30.
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Contributors: Prab R. Tumpati, MD
