Orbital lymphoma

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Orbital Lymphoma[edit | edit source]

Orbital lymphoma affecting the eye socket

Orbital lymphoma is a type of non-Hodgkin lymphoma that occurs in the orbit, the bony cavity in the skull where the eye and its appendages are situated. It is a rare condition that can affect the eye socket, leading to various ocular and systemic symptoms.

Pathophysiology[edit | edit source]

Orbital lymphoma is characterized by the proliferation of malignant lymphocytes within the orbital tissues. The most common type of orbital lymphoma is mucosa-associated lymphoid tissue (MALT) lymphoma, but other types such as diffuse large B-cell lymphoma and follicular lymphoma can also occur.

Clinical Presentation[edit | edit source]

Patients with orbital lymphoma may present with a variety of symptoms, including:

These symptoms result from the mass effect of the lymphoma within the confined space of the orbit.

Diagnosis[edit | edit source]

The diagnosis of orbital lymphoma typically involves:

Treatment[edit | edit source]

Treatment options for orbital lymphoma depend on the type and stage of the lymphoma and may include:

In some cases, a combination of these treatments may be used to achieve the best outcome.

Prognosis[edit | edit source]

The prognosis for patients with orbital lymphoma varies depending on the type and stage of the disease. MALT lymphoma generally has a good prognosis with appropriate treatment, while more aggressive types like diffuse large B-cell lymphoma may have a more guarded prognosis.

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Contributors: Prab R. Tumpati, MD