Ovarian suppression

Ovarian suppression is a medical treatment that prevents the ovaries from producing estrogen. This treatment is often used in women who have been diagnosed with hormone receptor-positive breast cancer, as it can help to slow the growth of the cancer cells. Ovarian suppression can be achieved through surgery, radiation, or medication.

Methods of Ovarian Suppression

Surgery

Oophorectomy is a surgical procedure that involves the removal of the ovaries. This procedure results in immediate ovarian suppression as it eliminates the primary source of estrogen production in the body.

Radiation

Radiation therapy can also be used to suppress ovarian function. This treatment involves the use of high-energy rays to damage or kill cancer cells.

Medication

Certain medications can be used to suppress the ovaries. These include gonadotropin-releasing hormone (GnRH) agonists, which work by blocking the signals that the body sends to the ovaries to produce estrogen.

Side Effects

Ovarian suppression can cause a number of side effects, including menopausal symptoms such as hot flashes, night sweats, and vaginal dryness. Other potential side effects include mood changes, decreased sexual desire, and bone loss.

See Also

• Breast cancer
• Hormone therapy
• Menopause

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